Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.76 |
| ▸ | MAP4K4 | O95819 | 12/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487674 | 1.00 | MET (0.76) | METMAP4K4HPGDRXRARXRB | |
| SCHEMBL30454009 | 0.92 | MET (0.65) | METMAP4K4 | |
| SCHEMBL487893 | 0.92 | MET (0.65) | METMAP4K4 | |
| SCHEMBL30453565 | 0.90 | MET (0.67) | METMAP4K4HPGD | |
| SCHEMBL487900 | 0.90 | MET (0.67) | METMAP4K4HPGD | |
| SCHEMBL30454971 | 0.87 | MAP4K4 (0.73) | METMAP4K4 | |
| SCHEMBL487832 | 0.87 | MAP4K4 (0.73) | METMAP4K4 | |
| SCHEMBL488515 | 0.87 | MET (0.62) | METMAP4K4HPGDRXRARXRB | |
| SCHEMBL487830 | 0.87 | MET (1.00) | METMAP4K4 | |
| SCHEMBL30453987 | 0.87 | MET (1.00) | METMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |