Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19400989 | 0.94 | CTSK (0.38) | CTSSCTSKAAK1CTSLCTSB | |
| SCHEMBL1864365 | 0.93 | CTSK (0.40) | CTSSCTSKAAK1CTSLCTSB | |
| SCHEMBL27994060 | 0.93 | CTSK (0.40) | CTSSCTSKAAK1CTSLCTSB | |
| SCHEMBL8002296 | 0.90 | CTSS (0.37) | CTSSCTSKCTSDCTSLCTSB | |
| SCHEMBL8077145 | 0.83 | PSEN1 (0.32) | CTSSCTSDCTSLCTSB | |
| SCHEMBL8004071 | 0.83 | PSEN1 (0.32) | CTSSCTSDCTSLCTSB | |
| SCHEMBL3263902 | 0.83 | PSEN1 (0.32) | CTSSCTSDCTSLCTSB | |
| SCHEMBL7998425 | 0.83 | PSEN1 (0.32) | CTSSCTSDCTSLCTSB | |
| SCHEMBL8075713 | 0.83 | PSEN1 (0.32) | CTSSCTSDCTSLCTSB | |
| SCHEMBL8079730 | 0.83 | PSEN1 (0.32) | CTSSCTSDCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669727-A | Triazole-pyridinyl substituted azacyclohexylacetic acid compounds as LPA receptor antagonists | 唯久生物有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4196220-A1 | TRIAZOLE-PYRIDINYL SUBSTITUTED AZACYCLOHEXYL ACETIC ACID COMPOUNDS AS LPA RECEPTOR ANTAGONISTS | Viva Star Biosciences Limited (HK) | 2023-06-21 | — | — | EP | disclosed |