Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.48 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22904552 | 0.88 | ITGB3 (0.46) | ITGB3ITGA2BCHRNA7CHRNA10CHRNA9 | |
| SCHEMBL30078285 | 0.86 | KDM4E (0.53) | ITGB3ITGA2BCYP3A4CHEK1USP2 | |
| SCHEMBL26648503 | 0.81 | ALDH1A1 (0.57) | CYP3A4USP2ALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL24832881 | 0.80 | ALDH1A1 (0.48) | ITGB3ITGA2BCYP3A4USP2ALDH1A1 | |
| SCHEMBL377181 | 0.79 | CHRNA7 (0.55) | ITGB3ITGA2BCHRNA7CHRNA10CHRNA9 | |
| SCHEMBL1377551 | 0.78 | CHRNA7 (0.54) | ITGB3ITGA2BCHRNA7CHRNA10CHRNA9 | |
| SCHEMBL3883363 | 0.76 | MAPT (0.61) | CHRNA7CHRNA10CHRNA9F2PRSS1 | |
| SCHEMBL4131556 | 0.76 | HRH3 (0.60) | ITGB3ITGA2BCHRNA7CHRNA10CHRNA9 | |
| SCHEMBL1397421 | 0.74 | NPC1 (0.61) | CHRNA7CHRNA10CHRNA9F2PRSS1 | |
| SCHEMBL4873981 | 0.74 | NPC1 (0.61) | CHRNA7CHRNA10CHRNA9F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121713-A1 | BCL-2 INHIBITORS | NEW AVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |