Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25355097 | 1.00 | ADRA2A (0.35) | ADRA2AMAP3K14NOS3NOS1NOS2 | |
| SCHEMBL4753561 | 0.82 | ADRA2A (0.50) | ADRA2A | |
| SCHEMBL13506581 | 0.79 | MAP3K14 (0.47) | ADRA2AMAP3K14NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL1162885 | 0.77 | HTR2C (0.35) | ADRA2ANOS3NOS1NOS2 | |
| SCHEMBL28970153 | 0.75 | KDM4C (0.36) | ADRA2AMAP3K14 | |
| SCHEMBL23976530 | 0.75 | KDM4C (0.36) | ADRA2AMAP3K14 | |
| SCHEMBL25351934 | 0.71 | ADRA2A (0.32) | ADRA2A | |
| SCHEMBL30782856 | 0.71 | ADRA2A (0.50) | ADRA2AMAP3K14 | |
| SCHEMBL14244555 | 0.71 | PRMT5 (0.35) | — | |
| SCHEMBL8238219 | 0.70 | CYP3A4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |