Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.72 |
| ▸ | MERTK | Q12866 | 3/20 | 0.46 |
| ▸ | AXL | P30530 | 2/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488428 | 1.00 | MET (0.72) | METMERTKAXLALKATR | |
| SCHEMBL30453919 | 0.90 | MET (0.83) | METMERTKAXL | |
| SCHEMBL488729 | 0.90 | MET (0.83) | METMERTKAXL | |
| SCHEMBL10217522 | 0.89 | MET (0.66) | METMERTKAXLALKATR | |
| SCHEMBL30452907 | 0.88 | MET (0.68) | METMERTKAXLALKATR | |
| SCHEMBL488638 | 0.88 | MET (0.68) | METMERTKAXLALKATR | |
| SCHEMBL5485033 | 0.87 | MET (0.74) | METMERTKAXLALKKCNH2 | |
| SCHEMBL10216184 | 0.87 | MET (0.79) | METMERTKAXLATRKDM4E | |
| SCHEMBL488118 | 0.86 | MET (0.91) | METMERTKAXLALKKCNH2 | |
| SCHEMBL30453588 | 0.86 | MET (0.91) | METMERTKAXLALKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |