Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.74 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.43 |
| ▸ | MAP4K5 | Q9Y4K4 | 3/20 | 0.43 |
| ▸ | MAP3K1 | Q13233 | 2/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.43 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.43 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.43 |
| ▸ | PLK4 | O00444 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | DCLK1 | O15075 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.43 |
| ▸ | INSR | P06213 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | FES | P07332 | 2/20 | 0.43 |
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
| ▸ | LYN | P07948 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488428 | 0.87 | MET (0.72) | METALKAXLKCNH2MERTK | |
| SCHEMBL30453490 | 0.87 | MET (0.72) | METALKAXLKCNH2MERTK | |
| SCHEMBL487888 | 0.86 | MET (1.00) | METMAP4K2MAP4K5MAP3K1AAK1 | |
| SCHEMBL30452784 | 0.86 | MET (1.00) | METMAP4K2MAP4K5MAP3K1AAK1 | |
| SCHEMBL30453919 | 0.83 | MET (0.83) | METJAK2AXLMERTK | |
| SCHEMBL488729 | 0.83 | MET (0.83) | METJAK2AXLMERTK | |
| SCHEMBL30453588 | 0.83 | MET (0.91) | METMAP4K2MAP4K5MAP3K1AAK1 | |
| SCHEMBL488118 | 0.83 | MET (0.91) | METMAP4K2MAP4K5MAP3K1AAK1 | |
| SCHEMBL30453639 | 0.82 | MET (0.85) | METMAP4K2MAP4K5MAP3K1AAK1 | |
| SCHEMBL488529 | 0.82 | MET (0.85) | METMAP4K2MAP4K5MAP3K1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072874-A1 | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN, INC. | 2007-03-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072874-A1 | Aminoheteroaryl compounds as protein kinase inhibitors | MET, MAP4K1, MAP4K2 | MET 1/4885MAP4K2 3/4885MAP4K5 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.