Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PDXK | O00764 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336213 | 1.00 | KEAP1 (0.47) | KEAP1NFE2L2KDM4EALDH1A1PDXK | |
| SCHEMBL31633211 | 0.85 | KDM4E (0.40) | KEAP1NFE2L2KDM4EALDH1A1PDXK | |
| SCHEMBL12506963 | 0.82 | ALDH1A1 (0.41) | KEAP1NFE2L2KDM4EALDH1A1PDXK | |
| SCHEMBL25354596 | 0.80 | KEAP1 (0.42) | KEAP1NFE2L2 | |
| SCHEMBL6222736 | 0.80 | KMT2A (0.47) | KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL15760104 | 0.79 | KEAP1 (0.41) | KEAP1NFE2L2KDM4EALDH1A1 | |
| SCHEMBL8235127 | 0.78 | KEAP1 (0.47) | KEAP1NFE2L2 | |
| SCHEMBL5044728 | 0.78 | KEAP1 (0.42) | KEAP1NFE2L2 | |
| SCHEMBL4882024 | 0.78 | KEAP1 (0.42) | KEAP1NFE2L2 | |
| SCHEMBL12413941 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |