Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 15/20 | 0.72 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.60 |
| ▸ | AXL | P30530 | 2/20 | 0.58 |
| ▸ | JAK2 | O60674 | 2/20 | 0.56 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.54 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.54 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.54 |
| ▸ | PLK4 | O00444 | 1/20 | 0.54 |
| ▸ | RIOK3 | O14730 | 1/20 | 0.54 |
| ▸ | IKBKB | O14920 | 1/20 | 0.54 |
| ▸ | CASK | O14936 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.54 |
| ▸ | MUSK | O15146 | 1/20 | 0.54 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.54 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.54 |
| ▸ | MLNR | O43193 | 1/20 | 0.54 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.54 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.54 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488320 | 1.00 | MET (0.72) | METALKAXLJAK2MAP4K3 | |
| SCHEMBL30453117 | 0.95 | MET (0.65) | METALKAXLJAK2MAP4K3 | |
| SCHEMBL488450 | 0.95 | MET (0.65) | METALKAXLJAK2MAP4K3 | |
| SCHEMBL10216571 | 0.92 | MET (0.72) | METALKAXLJAK2MAP4K3 | |
| SCHEMBL30453946 | 0.92 | MET (0.61) | METALKAXLJAK2 | |
| SCHEMBL488197 | 0.92 | MET (0.61) | METALKAXLJAK2 | |
| SCHEMBL10216591 | 0.91 | MET (0.71) | METALKAXLJAK2MAP4K3 | |
| SCHEMBL14492943 | 0.91 | MET (0.68) | METALKAXLJAK2MAP4K3 | |
| SCHEMBL10216691 | 0.91 | MET (0.68) | METALKAXLJAK2MAP4K3 | |
| SCHEMBL10216489 | 0.91 | MET (0.68) | METALKAXLJAK2MAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |