Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.51 |
| ▸ | ATR | Q13535 | 2/20 | 0.48 |
| ▸ | GRK5 | P34947 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488825 | 1.00 | MET (0.54) | METMAP4K4ATRGRK5PIK3CD | |
| SCHEMBL30452825 | 0.96 | MET (0.60) | METMAP4K4ATRGRK5PIK3CD | |
| SCHEMBL487974 | 0.96 | MET (0.60) | METMAP4K4ATRGRK5PIK3CD | |
| SCHEMBL488531 | 0.94 | MET (0.61) | METMAP4K4ATRCHEK2 | |
| SCHEMBL30453089 | 0.94 | MET (0.61) | METMAP4K4ATRCHEK2 | |
| SCHEMBL30454107 | 0.92 | MET (0.59) | METATRALKCHEK2 | |
| SCHEMBL488600 | 0.92 | MET (0.59) | METATRALKCHEK2 | |
| SCHEMBL488272 | 0.92 | MET (0.55) | METMAP4K4PIK3CDPIK3CGALK | |
| SCHEMBL30454831 | 0.92 | MET (0.55) | METMAP4K4PIK3CDPIK3CGALK | |
| SCHEMBL488466 | 0.91 | MET (0.53) | METMAP4K4ATRCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |