Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.55 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.49 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488272 | 1.00 | MET (0.55) | METALKMAP4K3MAP4K4CHEK2 | |
| SCHEMBL487974 | 0.96 | MET (0.60) | METALKMAP4K3MAP4K4CHEK2 | |
| SCHEMBL30452825 | 0.96 | MET (0.60) | METALKMAP4K3MAP4K4CHEK2 | |
| SCHEMBL30453330 | 0.94 | MET (0.62) | METMAP4K3MAP4K4CHEK2 | |
| SCHEMBL488485 | 0.94 | MET (0.62) | METMAP4K3MAP4K4CHEK2 | |
| SCHEMBL30454668 | 0.93 | MET (0.54) | METALKMAP4K3 | |
| SCHEMBL488904 | 0.93 | MET (0.54) | METALKMAP4K3 | |
| SCHEMBL488825 | 0.92 | MET (0.54) | METALKMAP4K4CHEK2PIK3CD | |
| SCHEMBL30453544 | 0.92 | MET (0.54) | METALKMAP4K4CHEK2PIK3CD | |
| SCHEMBL30453345 | 0.90 | MET (0.68) | METMAP4K3MAP4K4CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |