Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | MAP4K3 | Q8IVH8 | 5/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487739 | 1.00 | MET (0.77) | METSMN1; SMN2MAP4K4MPOMAP4K3 | |
| SCHEMBL487907 | 0.89 | MET (0.81) | METMAP4K4MPOMAP4K3JAK2 | |
| SCHEMBL487777 | 0.88 | MET (0.83) | METSMN1; SMN2MAP4K4MPOMAP4K3 | |
| Water SCHEMBL28121971 | 0.88 | MET (0.79) | METMAP4K4MPOMAP4K3JAK2 | |
| SCHEMBL30452701 | 0.87 | MET (0.70) | METSMN1; SMN2MAP4K4MPOMAP4K3 | |
| SCHEMBL488667 | 0.87 | MET (0.70) | METSMN1; SMN2MAP4K4MPOMAP4K3 | |
| SCHEMBL487830 | 0.87 | MET (1.00) | METMAP4K4MPOMAP4K3 | |
| SCHEMBL30453987 | 0.87 | MET (1.00) | METMAP4K4MPOMAP4K3 | |
| SCHEMBL488323 | 0.87 | MET (0.73) | METSMN1; SMN2MAP4K4MPOMAP4K3 | |
| SCHEMBL6364739 | 0.86 | MET (0.75) | METSMN1; SMN2MAP4K4MPOMAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |