Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.70 |
| ▸ | JAK2 | O60674 | 2/20 | 0.54 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.43 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488667 | 1.00 | MET (0.70) | METJAK2SGMS2FYNMPO | |
| SCHEMBL30453556 | 0.87 | MET (0.77) | METJAK2MPOSMN1; SMN2MAP4K3 | |
| SCHEMBL487739 | 0.87 | MET (0.77) | METJAK2MPOSMN1; SMN2MAP4K3 | |
| SCHEMBL488323 | 0.87 | MET (0.73) | METJAK2MPOSMN1; SMN2MAP4K3 | |
| SCHEMBL487907 | 0.87 | MET (0.81) | METJAK2FYNMPOMAP4K3 | |
| SCHEMBL488416 | 0.86 | MAP4K3 (0.54) | METJAK2SGMS2FYNMPO | |
| SCHEMBL30454968 | 0.86 | MAP4K3 (0.54) | METJAK2SGMS2FYNMPO | |
| Water SCHEMBL28121971 | 0.86 | MET (0.79) | METJAK2FYNMPOMAP4K3 | |
| SCHEMBL488258 | 0.85 | MET (0.77) | METJAK2MPOMAP4K3MAP4K4 | |
| SCHEMBL487572 | 0.85 | MET (0.73) | METJAK2FYNMPOMAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |