Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 4/20 | 0.55 |
| ▸ | CSF1R | P07333 | 2/20 | 0.46 |
| ▸ | BMPR1B | O00238 | 3/20 | 0.44 |
| ▸ | BMPR1A | P36894 | 3/20 | 0.44 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.44 |
| ▸ | MET | P08581 | 4/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488430 | 1.00 | ATR (0.55) | ATRCSF1RBMPR1BBMPR1AACVRL1 | |
| SCHEMBL30453845 | 0.91 | ATR (0.57) | ATRCSF1RBMPR1BBMPR1AACVRL1 | |
| SCHEMBL488497 | 0.91 | ATR (0.57) | ATRCSF1RBMPR1BBMPR1AACVRL1 | |
| SCHEMBL30452905 | 0.85 | MET (0.60) | ATRBMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL487528 | 0.85 | MET (0.60) | ATRBMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL30454532 | 0.84 | MET (0.54) | ATRMETCHEK2BTKHDAC4 | |
| SCHEMBL488073 | 0.84 | MET (0.54) | ATRMETCHEK2BTKHDAC4 | |
| SCHEMBL30453528 | 0.84 | KCNH2 (0.53) | ATRCSF1RMETAURKAAURKB | |
| SCHEMBL488017 | 0.84 | KCNH2 (0.53) | ATRCSF1RMETAURKAAURKB | |
| SCHEMBL30453304 | 0.83 | ATR (0.55) | ATRCSF1RBMPR1BBMPR1AACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |