Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 4/20 | 0.57 |
| ▸ | AXL | P30530 | 1/20 | 0.51 |
| ▸ | MERTK | Q12866 | 1/20 | 0.51 |
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | DCK | P27707 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.41 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488497 | 1.00 | ATR (0.57) | ATRAXLMERTKCSF1RNTRK1 | |
| SCHEMBL488430 | 0.91 | ATR (0.55) | ATRCSF1RMETGABRA5BMPR1B | |
| SCHEMBL30453567 | 0.91 | ATR (0.55) | ATRCSF1RMETGABRA5BMPR1B | |
| SCHEMBL487873 | 0.87 | AXL (0.57) | ATRAXLMERTKNTRK1NTRK3 | |
| SCHEMBL30453612 | 0.87 | AXL (0.57) | ATRAXLMERTKNTRK1NTRK3 | |
| SCHEMBL30452937 | 0.85 | ATR (0.53) | ATRAXLMERTKCSF1RNTRK1 | |
| SCHEMBL488822 | 0.85 | ATR (0.53) | ATRAXLMERTKCSF1RNTRK1 | |
| SCHEMBL488250 | 0.85 | ATR (0.56) | ATRAXLMERTKNTRK1NTRK3 | |
| SCHEMBL30454131 | 0.85 | ATR (0.56) | ATRAXLMERTKNTRK1NTRK3 | |
| SCHEMBL488217 | 0.84 | ATR (0.58) | ATRCSF1RMETMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |