Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.55 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.52 |
| ▸ | AXL | P30530 | 2/20 | 0.51 |
| ▸ | MERTK | Q12866 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | ATR | Q13535 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488572 | 1.00 | MET (0.55) | METALKAXLMERTKJAK2 | |
| SCHEMBL488197 | 0.95 | MET (0.61) | METALKAXLJAK2 | |
| SCHEMBL30453946 | 0.95 | MET (0.61) | METALKAXLJAK2 | |
| SCHEMBL30453117 | 0.92 | MET (0.65) | METALKAXLMERTKJAK2 | |
| SCHEMBL488450 | 0.92 | MET (0.65) | METALKAXLMERTKJAK2 | |
| SCHEMBL30453654 | 0.90 | MET (0.54) | METALKAXLMERTKJAK2 | |
| SCHEMBL487905 | 0.90 | MET (0.54) | METALKAXLMERTKJAK2 | |
| SCHEMBL30454131 | 0.87 | ATR (0.56) | METAXLMERTKATR | |
| SCHEMBL488250 | 0.87 | ATR (0.56) | METAXLMERTKATR | |
| SCHEMBL488320 | 0.87 | MET (0.72) | METALKAXLMERTKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |