Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 5/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.40 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22391649 | 1.00 | CNR1 (0.46) | CNR1GPR119PDK4GRM5GRM1 | |
| SCHEMBL24320571 | 0.89 | TLR7 (0.47) | CNR1GPR119PDK4GRM5GRM1 | |
| SCHEMBL22402442 | 0.88 | CNR1 (0.48) | CNR1PDK4GRM5GRM1HTR6 | |
| SCHEMBL31342210 | 0.85 | CNR1 (0.55) | CNR1PDK4GRM5GRM1HTR6 | |
| SCHEMBL15556190 | 0.85 | CNR1 (0.55) | CNR1PDK4GRM5GRM1HTR6 | |
| SCHEMBL31009243 | 0.84 | GRM1 (0.50) | CNR1GPR119PDK4GRM5GRM1 | |
| SCHEMBL31306920 | 0.84 | GRM1 (0.47) | CNR1GPR119GRM5GRM1CDK9 | |
| SCHEMBL30583911 | 0.83 | GRM5 (0.48) | CNR1GPR119GRM5GRM1CDK9 | |
| SCHEMBL22391814 | 0.82 | GRM5 (0.44) | CNR1GPR119PDK4GRM5GRM1 | |
| SCHEMBL30284525 | 0.82 | GRM5 (0.44) | CNR1GPR119PDK4GRM5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |