Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 8/20 | 0.50 |
| ▸ | GRM5 | P41594 | 8/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | EED | O75530 | 1/20 | 0.42 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.42 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.42 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30237145 | 0.88 | GRM5 (0.48) | GRM1GRM5PDE10APDK4GPR119 | |
| SCHEMBL24574672 | 0.88 | GRM5 (0.48) | GRM1GRM5PDE10APDK4GPR119 | |
| SCHEMBL26913997 | 0.85 | GRM1 (0.47) | GRM1GRM5CNR1GPR119 | |
| SCHEMBL22391649 | 0.84 | CNR1 (0.46) | GRM1GRM5PDK4CNR1DGAT2 | |
| SCHEMBL30453607 | 0.84 | CNR1 (0.46) | GRM1GRM5PDK4CNR1DGAT2 | |
| SCHEMBL30583911 | 0.84 | GRM5 (0.48) | GRM1GRM5PDE10ACNR1GPR119 | |
| SCHEMBL26913668 | 0.83 | GPR119 (0.44) | GRM1GRM5CNR1DGAT2CYP3A4 | |
| SCHEMBL4011353 | 0.82 | PDE10A (0.55) | GRM1GRM5PDE10APDK4CNR1 | |
| SCHEMBL31342210 | 0.82 | CNR1 (0.55) | GRM1GRM5PDK4CNR1CYP3A4 | |
| SCHEMBL15556190 | 0.82 | CNR1 (0.55) | GRM1GRM5PDK4CNR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4650353-A1 | 4-ALKOXY BENZIMIDAZOLE-6-CARBOXYLIC ACID DERIVATIVE SERVING AS GLP-1 RECEPTOR AGONIST | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2025-11-19 | — | — | EP | disclosed |
| CN-118344349-A | 4-Alkoxybenzimidazole-6-carboxylic acid derivatives as GLP-1 receptor agonists | 中国科学院上海药物研究所 | 2024-07-16 | — | — | CN | disclosed |