Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349765 | 0.87 | HRH3 (0.59) | LMNATDP1HRH3RAB9AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3716650 | 0.78 | HRH1 (0.68) | LMNATDP1L3MBTL1HTTALOX15 | |
| SCHEMBL3716649 | 0.78 | L3MBTL1 (0.64) | LMNATDP1L3MBTL1HTTHRH3 | |
| SCHEMBL1855946 | 0.77 | CHRM2 (0.53) | LMNATDP1HRH3ALDH1A1TAAR1 | |
| SCHEMBL4779999 | 0.77 | HRH1 (0.54) | LMNATDP1HRH3ALDH1A1TAAR1 | |
| Trifluoroacetic Acid SCHEMBL30169036 | 0.76 | ITGB3 (0.42) | L3MBTL1HTTRAB9ACYP1A2CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL28359404 | 0.74 | SMN1; SMN2 (0.52) | LMNATDP1RAB9AALDH1A1ALOX15 | |
| Trifluoroacetic Acid SCHEMBL27938747 | 0.74 | CYP1A2 (0.52) | LMNATDP1CYP1A2CYP2C19CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL20479965 | 0.74 | PTPRA (0.47) | RAB9ACYP1A2CYP2C19CYP2D6SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL9571825 | 0.74 | CYP1A2 (0.48) | RAB9AALDH1A1CYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |