Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 10/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.45 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488611 | 1.00 | MET (0.74) | METSLC6A2SLC6A4JAK2CHEK2 | |
| SCHEMBL30452893 | 0.95 | MET (0.81) | METJAK2CHEK2BMPR1BBMPR1A | |
| SCHEMBL488700 | 0.95 | MET (0.81) | METJAK2CHEK2BMPR1BBMPR1A | |
| SCHEMBL30453431 | 0.93 | MET (0.65) | METJAK2DRD4DRD2F10 | |
| SCHEMBL488344 | 0.93 | MET (0.65) | METJAK2DRD4DRD2F10 | |
| SCHEMBL487966 | 0.90 | MET (0.91) | METJAK2 | |
| SCHEMBL30453174 | 0.90 | MET (0.91) | METJAK2 | |
| SCHEMBL30453602 | 0.88 | MET (0.83) | METJAK2 | |
| SCHEMBL488253 | 0.88 | MET (0.83) | METJAK2 | |
| SCHEMBL30452523 | 0.88 | MET (0.71) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |