Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.81 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.50 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.50 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.50 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.50 |
| ▸ | ATR | Q13535 | 4/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488700 | 1.00 | MET (0.81) | METBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL488611 | 0.95 | MET (0.74) | METBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL30453655 | 0.95 | MET (0.74) | METBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL30452523 | 0.93 | MET (0.71) | METALDH1A1CD274 | |
| SCHEMBL488275 | 0.93 | MET (0.71) | METALDH1A1CD274 | |
| SCHEMBL30452645 | 0.93 | MET (0.71) | METATRJAK2 | |
| SCHEMBL488314 | 0.93 | MET (0.71) | METATRJAK2 | |
| SCHEMBL488644 | 0.92 | MET (0.70) | METBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL488439 | 0.90 | MET (1.00) | METJAK2 | |
| SCHEMBL30454945 | 0.90 | MET (1.00) | METJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |