Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 14/20 | 0.58 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.38 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488222 | 1.00 | MET (0.58) | METMAP4K3JAK2NPC1RAB9A | |
| SCHEMBL10215391 | 1.00 | MET (0.58) | METMAP4K3JAK2NPC1RAB9A | |
| SCHEMBL487998 | 0.91 | MET (0.69) | METMAP4K3JAK2 | |
| SCHEMBL30452803 | 0.91 | MET (0.69) | METMAP4K3JAK2 | |
| SCHEMBL10215375 | 0.91 | MET (0.69) | METMAP4K3JAK2 | |
| SCHEMBL10216291 | 0.86 | MET (0.48) | METMAP4K3 | |
| SCHEMBL30452844 | 0.86 | MET (0.48) | METMAP4K3 | |
| SCHEMBL487807 | 0.86 | MET (0.48) | METMAP4K3 | |
| SCHEMBL30453694 | 0.86 | MET (0.54) | METNPC1RAB9ASMN1; SMN2FYN | |
| SCHEMBL487934 | 0.86 | MET (0.54) | METNPC1RAB9ASMN1; SMN2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |