Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.49 |
| ▸ | DRD3 | P35462 | 15/20 | 0.46 |
| ▸ | DRD2 | P14416 | 11/20 | 0.46 |
| ▸ | DRD4 | P21917 | 10/20 | 0.44 |
| ▸ | HTR1A | P08908 | 6/20 | 0.43 |
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487848 | 1.00 | MET (0.49) | METDRD3DRD2DRD4HTR1A | |
| SCHEMBL487484 | 0.88 | MET (0.51) | METDRD3DRD2DRD4HTR1A | |
| SCHEMBL30452667 | 0.88 | MET (0.51) | METDRD3DRD2DRD4HTR1A | |
| SCHEMBL487541 | 0.86 | MET (0.60) | METDRD3DRD2DRD4HTR1A | |
| SCHEMBL30454277 | 0.86 | MET (0.60) | METDRD3DRD2DRD4HTR1A | |
| SCHEMBL487898 | 0.82 | MET (0.58) | METDRD3DRD2DRD4HTR1A | |
| SCHEMBL30452739 | 0.82 | MET (0.58) | METDRD3DRD2DRD4HTR1A | |
| SCHEMBL488203 | 0.80 | MET (0.61) | MET | |
| SCHEMBL30452997 | 0.80 | MET (0.61) | MET | |
| SCHEMBL489166 | 0.79 | MET (0.76) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |