Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 10/20 | 0.49 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ATR | Q13535 | 7/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | NPM1 | P06748 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30452577 | 1.00 | MET (0.49) | METMAP4K3KCNH2ATRCHEK2 | |
| SCHEMBL488013 | 1.00 | MET (0.49) | METMAP4K3KCNH2ATRCHEK2 | |
| SCHEMBL488683 | 1.00 | MET (0.49) | METMAP4K3KCNH2ATRCHEK2 | |
| SCHEMBL488014 | 1.00 | MET (0.49) | METMAP4K3KCNH2ATRCHEK2 | |
| SCHEMBL10216321 | 0.95 | MET (0.55) | METMAP4K3KCNH2CHEK2INSR | |
| SCHEMBL10216324 | 0.95 | MET (0.55) | METMAP4K3KCNH2CHEK2INSR | |
| SCHEMBL488688 | 0.92 | KCNH2 (0.55) | METMAP4K3KCNH2ATRCHEK2 | |
| SCHEMBL30452472 | 0.92 | KCNH2 (0.55) | METMAP4K3KCNH2ATRCHEK2 | |
| SCHEMBL488690 | 0.92 | KCNH2 (0.55) | METMAP4K3KCNH2ATRCHEK2 | |
| SCHEMBL10216401 | 0.90 | MET (0.50) | METMAP4K3KCNH2ATRCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |