Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | MET | P08581 | 15/20 | 0.54 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.49 |
| ▸ | ATR | Q13535 | 3/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.42 |
| ▸ | MAP3K1 | Q13233 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.42 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488690 | 1.00 | KCNH2 (0.55) | KCNH2METMAP4K3ATRCHEK2 | |
| SCHEMBL488688 | 1.00 | KCNH2 (0.55) | KCNH2METMAP4K3ATRCHEK2 | |
| SCHEMBL488683 | 0.92 | MET (0.49) | KCNH2METMAP4K3ATRCHEK2 | |
| SCHEMBL30453702 | 0.92 | MET (0.49) | KCNH2METMAP4K3ATRCHEK2 | |
| SCHEMBL30452577 | 0.92 | MET (0.49) | KCNH2METMAP4K3ATRCHEK2 | |
| SCHEMBL488014 | 0.92 | MET (0.49) | KCNH2METMAP4K3ATRCHEK2 | |
| SCHEMBL488013 | 0.92 | MET (0.49) | KCNH2METMAP4K3ATRCHEK2 | |
| SCHEMBL488804 | 0.88 | MAP4K3 (0.48) | KCNH2METMAP4K3ATRCHEK2 | |
| SCHEMBL30452953 | 0.88 | MAP4K3 (0.48) | KCNH2METMAP4K3ATRCHEK2 | |
| SCHEMBL10216410 | 0.88 | MAP4K3 (0.48) | KCNH2METMAP4K3ATRCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |