Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.48 |
| ▸ | MAP4K3 | Q8IVH8 | 3/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488598 | 1.00 | MET (0.55) | METMAP4K4MAP4K3AXLMERTK | |
| SCHEMBL10218151 | 0.91 | MET (0.56) | METMAP4K4MAP4K3AXLMERTK | |
| SCHEMBL10218367 | 0.90 | MET (0.57) | METMAP4K4MAP4K3AXLMERTK | |
| SCHEMBL30453566 | 0.88 | MAP4K4 (0.64) | METMAP4K4MAP4K3CCNCCDK8 | |
| SCHEMBL488686 | 0.88 | MAP4K4 (0.64) | METMAP4K4MAP4K3CCNCCDK8 | |
| SCHEMBL10218287 | 0.87 | MET (0.53) | METMAP4K4MAP4K3 | |
| SCHEMBL10218171 | 0.87 | MET (0.57) | METMAP4K4MAP4K3CCNCCDK8 | |
| SCHEMBL10218397 | 0.87 | MET (0.51) | METMAP4K4MAP4K3AXLMERTK | |
| SCHEMBL10218191 | 0.87 | MET (0.58) | METMAP4K4MAP4K3 | |
| SCHEMBL10218093 | 0.87 | MET (0.60) | METMAP4K4MAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |