Vimseltinib

Vimseltinib

SCHEMBL30453793

Cc1nc(-c2cnc(NC(C)C)n(C)c2=O)ccc1Oc1ccnc(-c2cnn(C)c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 20/20 1.00
▸ PDGFRA P16234 13/20 1.00
▸ PDGFRB P09619 6/20 1.00
▸ FLT3 P36888 3/20 1.00
▸ KIT P10721 3/20 1.00
▸ CYP2C9 P11712 2/20 1.00
▸ LCK P06239 1/20 1.00
▸ PTK6 Q13882 1/20 1.00
▸ KDR P35968 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Vimseltinib SCHEMBL16047448 1.00 CSF1R (1.00) CSF1RPDGFRAPDGFRBFLT3KIT
Vimseltinib SCHEMBL31615255 0.99 CSF1R (0.98) CSF1RPDGFRAPDGFRBFLT3KIT
SCHEMBL31741098 0.90 CSF1R (0.82) CSF1RPDGFRAPDGFRBFLT3KIT
SCHEMBL16046817 0.89 CSF1R (0.80) CSF1RPDGFRAPDGFRBFLT3KIT
SCHEMBL25909908 0.89 CSF1R (0.79) CSF1RPDGFRAPDGFRBFLT3KIT
SCHEMBL16046264 0.88 CSF1R (1.00) CSF1RPDGFRAPDGFRBFLT3KIT
SCHEMBL31741155 0.88 CSF1R (0.78) CSF1RPDGFRAPDGFRBFLT3KIT
SCHEMBL25909923 0.86 CSF1R (0.76) CSF1RPDGFRAPDGFRBFLT3KIT
SCHEMBL16048025 0.86 CSF1R (0.76) CSF1RPDGFRAPDGFRBFLT3KIT
SCHEMBL25909802 0.86 CSF1R (0.76) CSF1RPDGFRAPDGFRBFLT3KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103452-A1 SOLID STATE FORMS OF A KINASE INHIBITOR DECIPHERA PHARMACEUTICALS LLC (US) 2026-04-16 — — US disclosed
US-20260078107-A1 CSF-1R INHIBITORS AND METHODS OF USE THEREOF DECIPHERA PHARMACEUTICALS LLC (US) 2026-03-19 — — US disclosed
US-20260048052-A1 METHODS OF TREATING TENOSYNOVIAL GIANT CELL TUMORS DECIPHERA PHARMACEUTICALS LLC (US) 2026-02-19 — — US disclosed
US-12528787-B2 Solid state forms of a kinase inhibitor DECIPHERA PHARMACEUTICALS, LLC (US) 2026-01-20 — — US disclosed
US-20250243182-A1 SOLID STATE FORMS OF A KINASE INHIBITOR DECIPHERA PHARMACEUTICALS, LLC 2025-07-31 — — US disclosed
US-20250206720-A1 SOLID FORMS OF AN ULK INHIBITOR DECIPHERA PHARMACEUTICALS, LLC 2025-06-26 — — US disclosed
US-20250205236-A1 FORMULATIONS OF VIMSELTINIB DECIPHERA PHARMACEUTICALS, LLC 2025-06-26 — — US disclosed
WO-2025122952-A1 FORMULATIONS OF VIMSELTINIB DECIPHERA PHARMACEUTICALS, LLC (US) 2025-06-12 — — WO disclosed
WO-2025122942-A1 SOLID STATE FORMS OF A KINASE INHIBITOR DECIPHERA PHARMACEUTICALS, LLC (US) 2025-06-12 — — WO disclosed
WO-2025096349-A1 METHODS OF TREATING TENOSYNOVIAL GIANT CELL TUMORS DECIPHERA PHARMACEUTICALS, LLC (US) 2025-05-08 — — WO disclosed
WO-2025065747-A1 APPLICATION OF CSF1R INHIBITOR IN PREPARATION OF NK/T CELL LYMPHOMA TREATMENT DRUG 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 2025-04-03 — — WO disclosed
CN-117427166-B Application of CSF1R inhibitor in preparation of NK/T cell lymphoma therapeutic drug 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 2024-09-10 — — CN disclosed
CN-116283919-A Novel crystal form of Vimseltinib and preparation method thereof 上海皓元医药股份有限公司 2023-06-23 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243182-A1 SOLID STATE FORMS OF A KINASE INHIBITOR MAP3K19, MAP3K20, MAP3K1 CSF1R 1415/4885PDGFRA 744/4885PDGFRB 732/4885
US-20250206720-A1 SOLID FORMS OF AN ULK INHIBITOR ULK2, ULK1, ULK3 CSF1R 2918/4885PDGFRA 2951/4885PDGFRB 2583/4885
US-20260103452-A1 SOLID STATE FORMS OF A KINASE INHIBITOR CSF1R, FLT3, CSF3R CSF1R 1/4885PDGFRA 45/4885PDGFRB 35/4885
US-12528787-B2 Solid state forms of a kinase inhibitor CSF1R, FLT3, CSF3R CSF1R 1/4885PDGFRA 80/4885PDGFRB 53/4885
US-20260048052-A1 METHODS OF TREATING TENOSYNOVIAL GIANT CELL TUMORS CSF1R, CSF3R, FLT1 CSF1R 1/4885PDGFRA 75/4885PDGFRB 83/4885
US-20260078107-A1 CSF-1R INHIBITORS AND METHODS OF USE THEREOF CSF1R, CSF3R, FLT3 CSF1R 1/4885PDGFRA 123/4885PDGFRB 100/4885
US-20250205236-A1 FORMULATIONS OF VIMSELTINIB KDR, VIM, UGT1A7 CSF1R 187/4885PDGFRA 14/4885PDGFRB 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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