Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30454256 | 0.82 | MAPK8 (0.33) | — | |
| SCHEMBL30453854 | 0.80 | MAPK8 (0.31) | — | |
| SCHEMBL30453940 | 0.79 | MAPK8 (0.34) | — | |
| SCHEMBL589718 | 0.75 | METAP2 (0.37) | METAP2 | |
| SCHEMBL31672509 | 0.74 | KDR (0.41) | METAP2 | |
| SCHEMBL10151182 | 0.74 | KDR (0.41) | METAP2 | |
| SCHEMBL12808485 | 0.71 | KDM4E (0.36) | METAP2 | |
| SCHEMBL30453669 | 0.66 | — | — | |
| SCHEMBL30453450 | 0.65 | LRRK2 (0.34) | — | |
| SCHEMBL30452600 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |