Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.63 |
| ▸ | MET | P08581 | 3/20 | 0.58 |
| ▸ | L3MBTL3 | Q96JM7 | 10/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.52 |
| ▸ | MBTD1 | Q05BQ5 | 6/20 | 0.52 |
| ▸ | MERTK | Q12866 | 2/20 | 0.52 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.50 |
| ▸ | L3MBTL4 | Q8NA19 | 2/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | ATR | Q13535 | 1/20 | 0.49 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488553 | 1.00 | MAP4K4 (0.63) | MAP4K4METL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL10217969 | 0.84 | MET (0.57) | MAP4K4METL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL30452977 | 0.84 | MET (0.66) | MAP4K4METL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL488613 | 0.84 | MET (0.66) | MAP4K4METL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL10217467 | 0.84 | MET (0.56) | MAP4K4METL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL10216178 | 0.84 | MET (0.63) | MAP4K4METL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL10217475 | 0.83 | MET (0.62) | MAP4K4METL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL10217559 | 0.83 | MET (0.56) | MAP4K4METL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL10217429 | 0.83 | MET (0.60) | MAP4K4METL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL10217502 | 0.83 | MET (0.62) | MAP4K4METL3MBTL3L3MBTL1MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |