Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.65 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.50 |
| ▸ | ITK | Q08881 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | MERTK | Q12866 | 1/20 | 0.45 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487799 | 1.00 | MET (0.65) | METMAP4K4KCNH2ITKABL1 | |
| SCHEMBL30454669 | 0.93 | MET (0.65) | METMAP4K4KCNH2ABL1BCR | |
| SCHEMBL488365 | 0.93 | MET (0.65) | METMAP4K4KCNH2ABL1BCR | |
| SCHEMBL487936 | 0.84 | MET (0.63) | METMAP4K4KCNH2 | |
| SCHEMBL10215335 | 0.84 | MET (0.63) | METMAP4K4KCNH2 | |
| SCHEMBL30453358 | 0.84 | MET (0.63) | METMAP4K4KCNH2 | |
| SCHEMBL488616 | 0.83 | MAP4K4 (0.75) | METMAP4K4XDH | |
| SCHEMBL30453341 | 0.83 | MAP4K4 (0.75) | METMAP4K4XDH | |
| SCHEMBL488146 | 0.80 | MET (0.63) | METMAP4K4KCNH2MAP3K11HPGD | |
| SCHEMBL30453233 | 0.80 | MET (0.63) | METMAP4K4KCNH2MAP3K11HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |