Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 8/20 | 0.75 |
| ▸ | MET | P08581 | 2/20 | 0.61 |
| ▸ | XDH | P47989 | 2/20 | 0.58 |
| ▸ | RXRA | P19793 | 3/20 | 0.57 |
| ▸ | RXRB | P28702 | 3/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.57 |
| ▸ | RXRG | P48443 | 2/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488616 | 1.00 | MAP4K4 (0.75) | MAP4K4METXDHRXRARXRB | |
| SCHEMBL30452762 | 0.87 | MET (0.56) | MAP4K4METXDHNR4A2NR4A1 | |
| SCHEMBL488223 | 0.87 | MET (0.56) | MAP4K4METXDHNR4A2NR4A1 | |
| SCHEMBL10214993 | 0.86 | MAP4K4 (1.00) | MAP4K4METXDHRXRARXRB | |
| SCHEMBL30454669 | 0.83 | MET (0.65) | MAP4K4METRAB9A | |
| SCHEMBL488365 | 0.83 | MET (0.65) | MAP4K4METRAB9A | |
| SCHEMBL30453882 | 0.83 | MET (0.65) | MAP4K4METXDH | |
| SCHEMBL487799 | 0.83 | MET (0.65) | MAP4K4METXDH | |
| SCHEMBL27650357 | 0.82 | MET (0.51) | MAP4K4METXDHRAB9AL3MBTL1 | |
| SCHEMBL28121929 | 0.82 | MAP4K4 (0.55) | MAP4K4METXDHRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |