Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.60 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487786 | 1.00 | MET (0.60) | METTBK1MPONPC1RAB9A | |
| SCHEMBL6425489 | 0.80 | CYP19A1 (0.47) | TBK1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL487907 | 0.80 | MET (0.81) | METMPOPRKDCMAP4K3CSF1R | |
| SCHEMBL488040 | 0.79 | MET (0.65) | METTBK1MPOMEN1KMT2A | |
| Water SCHEMBL28121971 | 0.78 | MET (0.79) | METMPOPRKDCMAP4K3CSF1R | |
| SCHEMBL487767 | 0.77 | MET (0.65) | METMPONPC1CYP2C9 | |
| SCHEMBL487777 | 0.76 | MET (0.83) | METMPOPRKDCMAP4K3CSF1R | |
| SCHEMBL27650107 | 0.76 | MET (0.60) | METMPOPRKDCMAP4K3CSF1R | |
| SCHEMBL488238 | 0.75 | MET (0.66) | METMPONPC1RAB9AMAPT | |
| SCHEMBL30453970 | 0.75 | MET (0.66) | METMPONPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |