Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488238 | 1.00 | MET (0.66) | METNPC1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL30453451 | 0.88 | MAP4K3 (0.53) | METNPC1SMN1; SMN2HTTCSF1R | |
| SCHEMBL488849 | 0.88 | MAP4K3 (0.53) | METNPC1SMN1; SMN2HTTCSF1R | |
| SCHEMBL487907 | 0.84 | MET (0.81) | METCSF1RMAP4K4MPOMAP4K3 | |
| SCHEMBL30453706 | 0.83 | MET (0.46) | METNPC1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL488033 | 0.83 | MET (0.46) | METNPC1SMN1; SMN2HTTL3MBTL1 | |
| Water SCHEMBL28121971 | 0.83 | MET (0.79) | METCSF1RMAP4K4MPOMAP4K3 | |
| SCHEMBL488281 | 0.82 | MAP4K3 (0.49) | METNPC1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL30454994 | 0.82 | MAP4K3 (0.49) | METNPC1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL487739 | 0.82 | MET (0.77) | METNPC1SMN1; SMN2CSF1RMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |