Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.68 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.51 |
| ▸ | MET | P08581 | 2/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487917 | 1.00 | MAP4K4 (0.68) | MAP4K4MAP4K3LTA4HMAPK14ALOX5AP | |
| SCHEMBL488178 | 0.88 | MAP4K4 (0.75) | MAP4K4MAP4K3LTA4HMAPK14ALOX5AP | |
| SCHEMBL30454152 | 0.86 | MAP4K4 (0.59) | MAP4K4MAP4K3LTA4HMETMPO | |
| SCHEMBL488102 | 0.86 | MAP4K4 (0.59) | MAP4K4MAP4K3LTA4HMETMPO | |
| SCHEMBL487854 | 0.86 | MAP4K4 (0.76) | MAP4K4MAP4K3LTA4HMAPK14ALOX5AP | |
| SCHEMBL30452754 | 0.86 | MAP4K4 (0.76) | MAP4K4MAP4K3LTA4HMAPK14ALOX5AP | |
| SCHEMBL30453373 | 0.83 | CYP11B1 (0.63) | MAP4K4MAP4K3LTA4HMAPK14MET | |
| SCHEMBL488124 | 0.83 | CYP11B1 (0.63) | MAP4K4MAP4K3LTA4HMAPK14MET | |
| SCHEMBL487829 | 0.83 | MAP4K4 (0.64) | MAP4K4MAP4K3LTA4HMAPK14ALOX5AP | |
| SCHEMBL10214993 | 0.81 | MAP4K4 (1.00) | MAP4K4METFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |