Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.63 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.63 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.62 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 2/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488124 | 1.00 | CYP11B1 (0.63) | CYP11B1CYP11B2CYP19A1MAP4K4LTA4H | |
| SCHEMBL488178 | 0.89 | MAP4K4 (0.75) | CYP11B1CYP11B2CYP19A1MAP4K4LTA4H | |
| SCHEMBL488296 | 0.88 | MAP4K3 (0.52) | CYP11B1CYP11B2CYP19A1MAP4K4LTA4H | |
| SCHEMBL30453298 | 0.88 | MAP4K3 (0.52) | CYP11B1CYP11B2CYP19A1MAP4K4LTA4H | |
| SCHEMBL487829 | 0.86 | MAP4K4 (0.64) | CYP11B1CYP11B2CYP19A1MAP4K4LTA4H | |
| SCHEMBL14259206 | 0.84 | CYP11B1 (0.63) | CYP11B1CYP11B2CYP19A1MAP4K4LTA4H | |
| SCHEMBL30453947 | 0.83 | MAP4K4 (0.68) | CYP11B1CYP11B2CYP19A1MAP4K4LTA4H | |
| SCHEMBL487917 | 0.83 | MAP4K4 (0.68) | CYP11B1CYP11B2CYP19A1MAP4K4LTA4H | |
| SCHEMBL30454968 | 0.82 | MAP4K3 (0.54) | CYP11B1CYP11B2CYP19A1MAP4K4MAP4K3 | |
| SCHEMBL488416 | 0.82 | MAP4K3 (0.54) | CYP11B1CYP11B2CYP19A1MAP4K4MAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |