Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.76 |
| ▸ | MET | P08581 | 2/20 | 0.66 |
| ▸ | USP7 | Q93009 | 2/20 | 0.58 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 3/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487854 | 1.00 | MAP4K4 (0.76) | MAP4K4METUSP7MAP4K3LTA4H | |
| SCHEMBL488178 | 0.91 | MAP4K4 (0.75) | MAP4K4METUSP7MAP4K3LTA4H | |
| SCHEMBL10214993 | 0.87 | MAP4K4 (1.00) | MAP4K4MET | |
| SCHEMBL487917 | 0.86 | MAP4K4 (0.68) | MAP4K4METMAP4K3LTA4HMAPK14 | |
| SCHEMBL30453947 | 0.86 | MAP4K4 (0.68) | MAP4K4METMAP4K3LTA4HMAPK14 | |
| SCHEMBL487829 | 0.83 | MAP4K4 (0.64) | MAP4K4METMAP4K3LTA4HMAPK14 | |
| SCHEMBL30452762 | 0.83 | MET (0.56) | MAP4K4METUSP7MAP4K3FYN | |
| SCHEMBL488223 | 0.83 | MET (0.56) | MAP4K4METUSP7MAP4K3FYN | |
| SCHEMBL488015 | 0.82 | MAP4K4 (0.78) | MAP4K4METMAP4K3CHEK2LMNA | |
| SCHEMBL30452824 | 0.81 | MET (0.75) | MAP4K4METUSP7MAP4K3FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |