Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 8/20 | 0.65 |
| ▸ | MAP4K4 | O95819 | 8/20 | 0.64 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487893 | 1.00 | MET (0.65) | METMAP4K4ALKBH1SMN1; SMN2FEN1 | |
| SCHEMBL487688 | 0.92 | MAP4K4 (0.71) | METMAP4K4ALKBH1FEN1 | |
| SCHEMBL30454464 | 0.92 | MAP4K4 (0.71) | METMAP4K4ALKBH1FEN1 | |
| SCHEMBL487674 | 0.92 | MET (0.76) | METMAP4K4 | |
| SCHEMBL30453780 | 0.92 | MET (0.76) | METMAP4K4 | |
| SCHEMBL487969 | 0.88 | MET (0.84) | METMAP4K4SMN1; SMN2 | |
| SCHEMBL30453384 | 0.88 | MET (0.84) | METMAP4K4SMN1; SMN2 | |
| SCHEMBL488145 | 0.88 | MET (0.68) | METMAP4K4SMN1; SMN2TP53 | |
| SCHEMBL488594 | 0.88 | MAP4K4 (0.61) | METMAP4K4 | |
| SCHEMBL487982 | 0.87 | MAP4K4 (0.64) | METMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |