Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | F13A1 | P00488 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | TGM1 | P22735 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5857969 | 1.00 | MAPK1 (0.64) | MAPK1SMN1; SMN2RAB9ANPC1CYP2C19 | |
| SCHEMBL25222541 | 0.88 | MAPK1 (0.49) | MAPK1SMN1; SMN2RAB9ANPC1CYP2C19 | |
| SCHEMBL30461706 | 0.88 | MAPK1 (0.49) | MAPK1SMN1; SMN2RAB9ANPC1CYP2C19 | |
| SCHEMBL4910166 | 0.88 | LMNA (0.63) | MAPK1SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL22391948 | 0.83 | MEN1 (0.59) | SMN1; SMN2RAB9ANPC1CYP2C19ALDH1A1 | |
| SCHEMBL3992139 | 0.82 | MAPK1 (0.65) | MAPK1RAB9ACYP2C19MAPTALDH1A1 | |
| SCHEMBL3992132 | 0.82 | MAPK1 (0.65) | MAPK1RAB9ACYP2C19MAPTALDH1A1 | |
| SCHEMBL5857295 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B | |
| SCHEMBL21752587 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1CYP2C19MAPT | |
| SCHEMBL31391643 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |