Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.49 |
| ▸ | BMPR1B | O00238 | 3/20 | 0.48 |
| ▸ | BMPR1A | P36894 | 3/20 | 0.48 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.46 |
| ▸ | AXL | P30530 | 3/20 | 0.46 |
| ▸ | MERTK | Q12866 | 3/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488735 | 1.00 | MET (0.49) | METBMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL487889 | 0.88 | MET (0.61) | METBMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL30453516 | 0.88 | MET (0.61) | METBMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL30453653 | 0.85 | ATR (0.54) | METPTK2SLC6A5AXLMERTK | |
| SCHEMBL487938 | 0.85 | ATR (0.54) | METPTK2SLC6A5AXLMERTK | |
| SCHEMBL488288 | 0.85 | KCNH2 (0.56) | METBMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL30454652 | 0.85 | KCNH2 (0.56) | METBMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL488715 | 0.85 | MET (0.48) | METBMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL30452899 | 0.85 | MET (0.48) | METBMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL30454861 | 0.83 | MET (0.61) | METBMPR1BBMPR1AACVRL1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |