SCHEMBL30454432

SCHEMBL30454432

CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ OPRK1 P41145 6/20 0.53
▸ ACE P12821 5/20 0.51
▸ ACE2 Q9BYF1 4/20 0.51
▸ F2R P25116 2/20 0.51
▸ CTSD P07339 2/20 0.51
▸ CTSE P14091 2/20 0.51
▸ BACE1 P56817 1/20 0.51
▸ NMUR2 Q9GZQ4 2/20 0.49
▸ NMUR1 Q9HB89 2/20 0.49
▸ REN P00797 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29666880 0.90 OPRK1 (0.58) OPRK1ACEACE2NMUR2NMUR1
SCHEMBL29666769 0.90 ACE (0.58) ACEACE2
SCHEMBL29666805 0.90 CALCRL (0.55) OPRK1ACEACE2
SCHEMBL29666745 0.89 ACE (0.58) ACEACE2
SCHEMBL29666860 0.88 ACE (0.57) OPRK1ACEACE2REN
SCHEMBL30785955 0.86 ACE (0.56) OPRK1ACEACE2
SCHEMBL30203894 0.86 NMUR2 (0.54) OPRK1NMUR2NMUR1
SCHEMBL29666711 0.85 ACE (0.59) OPRK1ACEACE2
SCHEMBL29666878 0.85 ACE (0.58) ACEACE2
SCHEMBL29666773 0.84 ACE (0.59) ACEACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023122721-A2 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA OREGON STATE UNIVERSITY (US) 2023-06-29 — — WO claimed
US-20240343760-A1 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA OREGON STATE UNIVERSITY (OR) 2024-10-17 — — US disclosed
WO-2023122721-A2 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA OREGON STATE UNIVERSITY (US) 2023-06-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240343760-A1 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA ARGLU1, TPX2, RXFP1 OPRK1 1864/4885ACE 3897/4885ACE2 3468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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