Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 10/20 | 0.54 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.52 |
| ▸ | JAK2 | O60674 | 7/20 | 0.48 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488071 | 1.00 | MET (0.54) | METALKJAK2JAK1TYK2 | |
| SCHEMBL488671 | 0.86 | MET (0.71) | METALKJAK2AXL | |
| SCHEMBL30454554 | 0.86 | MET (0.71) | METALKJAK2AXL | |
| SCHEMBL27650246 | 0.84 | KDM4E (0.43) | AXL | |
| SCHEMBL487940 | 0.81 | ALK (0.72) | METALKJAK2AXL | |
| SCHEMBL30453916 | 0.81 | ALK (0.72) | METALKJAK2AXL | |
| SCHEMBL30453722 | 0.79 | ALK (0.80) | METALKJAK2AXL | |
| SCHEMBL488401 | 0.79 | ALK (0.80) | METALKJAK2AXL | |
| SCHEMBL21478607 | 0.78 | JAK2 (0.55) | ALKJAK2JAK1TYK2JAK3 | |
| SCHEMBL488800 | 0.77 | ALK (0.70) | METALKJAK2AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |