Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.60 |
| ▸ | AKT2 | P31751 | 3/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.54 |
| ▸ | CDK2 | P24941 | 2/20 | 0.54 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.54 |
| ▸ | TLK2 | Q86UE8 | 3/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30453243 | 0.87 | PDPK1 (0.60) | PDPK1AKT2AURKARAF1MEN1 | |
| SCHEMBL3799498 | 0.86 | AKT2 (0.67) | PDPK1AKT2CCNE1CDK2CCNE2 | |
| SCHEMBL31216363 | 0.79 | KDR (0.71) | PDPK1AKT2TLK2AURKAMEN1 | |
| SCHEMBL2114561 | 0.79 | PAK4 (0.57) | PDPK1AKT2TLK2AURKAMEN1 | |
| SCHEMBL1965178 | 0.78 | AURKA (0.69) | PDPK1TLK2AURKARAF1MEN1 | |
| SCHEMBL12580695 | 0.78 | AURKA (0.69) | PDPK1TLK2AURKARAF1MEN1 | |
| SCHEMBL2115629 | 0.78 | AKT2 (0.53) | PDPK1AKT2TLK2AURKAMEN1 | |
| SCHEMBL5728671 | 0.75 | PDPK1 (1.00) | PDPK1TLK2KDRNTRK1 | |
| SCHEMBL5361523 | 0.75 | PDPK1 (1.00) | PDPK1TLK2KDRNTRK1 | |
| SCHEMBL3284152 | 0.74 | FLT3 (0.68) | PDPK1CCNE1CDK2CCNE2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |