Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3551505 | 0.91 | GRIN1 (0.30) | GRIN1GRIN2B | |
| SCHEMBL3045454 | 0.79 | JAK2 (0.34) | GRIN1GRIN2B | |
| SCHEMBL2768740 | 0.78 | NLRP3 (0.30) | — | |
| SCHEMBL2769080 | 0.77 | NLRP3 (0.32) | — | |
| SCHEMBL2769844 | 0.77 | NLRP3 (0.30) | — | |
| SCHEMBL2765879 | 0.76 | KCNA5 (0.30) | — | |
| SCHEMBL2767096 | 0.76 | NLRP3 (0.30) | — | |
| SCHEMBL2767659 | 0.76 | KDM4E (0.31) | — | |
| SCHEMBL2768319 | 0.75 | NLRP3 (0.31) | — | |
| SCHEMBL12344514 | 0.75 | IKBKB (0.35) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210629-A1 | 1,6-DIHYDRO-1,3,5,6-TETRAAZA-AS-INDACENE BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | BRISTOL-MYERS SQUIBB COMPANY | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210629-A1 | 1,6-DIHYDRO-1,3,5,6-TETRAAZA-AS-INDACENE BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | IL1R1, IDO1, TLR1 | GRIN1 2026/4885GRIN2B 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.