Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16560286 | 1.00 | LMNA (0.48) | LMNAADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL14373886 | 1.00 | LMNA (0.48) | LMNAADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL808662 | 1.00 | LMNA (0.48) | LMNAADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL17947385 | 0.84 | LMNA (0.45) | LMNAADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL20202580 | 0.84 | LMNA (0.45) | LMNAADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL8257922 | 0.84 | LMNA (0.45) | LMNAADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL31607076 | 0.83 | ADRB1 (0.47) | ADRB1ADRA2AADRB3ADRA2BADRA2C | |
| SCHEMBL23231419 | 0.82 | LMNA (0.44) | LMNAADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL18406260 | 0.82 | LMNA (0.44) | LMNAADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL8282358 | 0.82 | LMNA (0.44) | LMNAADRB1ADRA2AADRB3ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |