Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413959 | 1.00 | TLR8 (0.37) | TLR8ALDH1A1KDM4ECYP3A4MAPK1 | |
| SCHEMBL7955099 | 0.82 | CYP2A6 (0.41) | TLR8ALDH1A1KDM4ECYP3A4MAPK1 | |
| SCHEMBL8291834 | 0.79 | ALDH1A1 (0.37) | TLR8ALDH1A1KDM4ECYP3A4MAOA | |
| SCHEMBL8267507 | 0.78 | TLR8 (0.58) | TLR8ALDH1A1KDM4EMAOAMAPT | |
| SCHEMBL7397919 | 0.78 | TLR8 (0.36) | TLR8ALDH1A1KDM4ECYP3A4MAPK1 | |
| SCHEMBL16650194 | 0.77 | KDM4E (0.40) | TLR8ALDH1A1KDM4ECYP3A4MAPK1 | |
| SCHEMBL659828 | 0.76 | TLR8 (0.33) | TLR8ALDH1A1CYP3A4MAPK1MAPT | |
| SCHEMBL1849913 | 0.73 | CYP2A6 (0.43) | TLR8ALDH1A1CYP3A4MAPK1MAPT | |
| SCHEMBL4420514 | 0.73 | ALDH1A1 (0.45) | ALDH1A1KDM4ECYP3A4MAPK1MAOA | |
| SCHEMBL21999291 | 0.72 | TLR8 (0.44) | TLR8ALDH1A1LMNACYP2A6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |