Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18195342 | 0.88 | ALDH1A1 (0.43) | ALDH1A1MAOACA1CA9TDP1 | |
| SCHEMBL15851174 | 0.87 | ALDH1A1 (0.41) | ALDH1A1MAOACA1CA9TDP1 | |
| SCHEMBL18133619 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MAOACA1CA9TDP1 | |
| SCHEMBL12279379 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MAOACA1CA9TDP1 | |
| SCHEMBL4430567 | 0.84 | MAOA (0.41) | ALDH1A1MAOACYP1A2KDM4ECYP3A4 | |
| SCHEMBL24858080 | 0.81 | ALDH1A1 (0.34) | ALDH1A1MAOACA1CA9TDP1 | |
| SCHEMBL28417210 | 0.81 | CYP3A4 (0.47) | ALDH1A1MAOACA9CYP1A2KDM4E | |
| SCHEMBL30009780 | 0.79 | KMT2A (0.51) | ALDH1A1MAOATDP1CYP1A2KDM4E | |
| SCHEMBL4428324 | 0.78 | MAOB (0.58) | ALDH1A1MAOACYP1A2ADORA2ACYP2A6 | |
| SCHEMBL18267849 | 0.77 | ALDH1A1 (0.36) | ALDH1A1MAOACYP1A2KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351266-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-04-01 | — | — | US | claimed |
| US-20050193504-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-08 | — | — | US | claimed |
| US-9236613-B2 | Cyclic compound, its metal complex and modified metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-01-12 | — | — | US | disclosed |
| US-9236613-B2 | Cyclic compound, its metal complex and modified metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-01-12 | — | — | US | disclosed |
| US-9130233-B2 | Metal complex, modified compound thereof and useful compound thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-09-08 | — | — | US | disclosed |
| US-9130233-B2 | Metal complex, modified compound thereof and useful compound thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-09-08 | — | — | US | disclosed |
| US-8546291-B2 | Cyclic compound, its metal complex and modified metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-10-01 | — | — | US | disclosed |
| US-8546291-B2 | Cyclic compound, its metal complex and modified metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20130210615-A1 | METAL COMPLEX, MODIFIED COMPOUND THEREOF AND USEFUL COMPOUND THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-15 | — | — | US | disclosed |
| US-20130210615-A1 | METAL COMPLEX, MODIFIED COMPOUND THEREOF AND USEFUL COMPOUND THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-15 | — | — | US | disclosed |
| US-8329929-B2 | Metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-11 | — | — | US | disclosed |
| US-20090318681-A1 | METAL COMPLEX, AND USE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090318681-A1 | METAL COMPLEX, AND USE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2123638-A1 | METAL COMPLEX | Sumitomo Chemical Company, Limited (JP) | 2009-11-25 | — | — | EP | disclosed |
| US-7468080-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-12-23 | — | — | US | disclosed |
| US-20080134450-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | WELLA OPERATIONS US, LLC | 2008-06-12 | — | — | US | disclosed |
| US-7351266-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-04-01 | — | — | US | disclosed |
| EP-1720615-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005087187-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-09-22 | — | — | WO | disclosed |
| US-20050193504-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050193504-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, CKMT1A; CKMT1B, KRTCAP2 | ALDH1A1 657/4885MAOA 507/4885CA1 1514/4885 |
| US-20080134450-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | KRT18, CKMT1A; CKMT1B, KRTCAP2 | ALDH1A1 657/4885MAOA 507/4885CA1 1514/4885 |
| US-20130210615-A1 | METAL COMPLEX, MODIFIED COMPOUND THEREOF AND USEFUL COMPOUND THEREOF | C5, PRMT1, C1QBP | ALDH1A1 1546/4885MAOA 912/4885CA1 71/4885 |
| US-20090318681-A1 | METAL COMPLEX, AND USE THEREOF | MT-CO1, CYC1, ACAD9 | ALDH1A1 225/4885MAOA 346/4885CA1 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.