Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057291 | 0.71 | HDAC1 (0.50) | TLR9POLBKDM4EALDH1A1TDP1 | |
| Formic Acid SCHEMBL30455255 | 0.71 | HRH3 (0.37) | KDM4EALDH1A1NPC1GAATP53 | |
| SCHEMBL13080648 | 0.70 | KDM4E (0.48) | POLBKDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL20713617 | 0.67 | PTGS1 (0.47) | POLBKDM4EALDH1A1NPC1GAA | |
| SCHEMBL13050352 | 0.67 | TP53 (0.38) | TLR9POLBKDM4ETLR7ALDH1A1 | |
| SCHEMBL4346992 | 0.66 | KDM4E (0.44) | POLBKDM4EALDH1A1TDP1L3MBTL1 | |
| Bromide SCHEMBL4347296 | 0.66 | PTGS1 (0.58) | POLBKDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL20049150 | 0.64 | HDAC4 (0.47) | POLBKDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL17437886 | 0.63 | KDM4E (0.78) | POLBKDM4EALDH1A1NPC1GAA | |
| SCHEMBL21835387 | 0.63 | KDM4E (0.43) | POLBKDM4EALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143708-A | Polysubstituted benzazepine heteroaryl derivative and application thereof | 四川汇宇制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |