Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.68 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HKDC1 | Q2TB90 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29882877 | 0.89 | TOP2A (0.67) | TOP2ASLC2A1HSP90AA1SMN1; SMN2RAB9A | |
| SCHEMBL29723632 | 0.89 | TOP2A (0.67) | TOP2ASLC2A1HSP90AA1SMN1; SMN2RAB9A | |
| SCHEMBL5839502 | 0.89 | TOP2A (0.67) | TOP2ASLC2A1HSP90AA1SMN1; SMN2RAB9A | |
| SCHEMBL17207742 | 0.89 | TOP2A (0.67) | TOP2ASLC2A1HSP90AA1SMN1; SMN2RAB9A | |
| SCHEMBL17987719 | 0.81 | TOP2A (1.00) | TOP2ASLC2A1HSP90AA1SMN1; SMN2RAB9A | |
| SCHEMBL29883013 | 0.81 | TOP2A (1.00) | TOP2ASLC2A1HSP90AA1SMN1; SMN2RAB9A | |
| SCHEMBL9321802 | 0.81 | TOP2A (1.00) | TOP2ASLC2A1HSP90AA1SMN1; SMN2RAB9A | |
| SCHEMBL9120443 | 0.81 | TOP2A (0.60) | TOP2ASLC2A1HSP90AA1SMN1; SMN2RAB9A | |
| SCHEMBL22056136 | 0.80 | TOP2A (0.76) | TOP2ASLC2A1HSP90AA1SMN1; SMN2RAB9A | |
| SCHEMBL9123460 | 0.79 | AGTR1 (0.62) | TOP2ASLC2A1SMN1; SMN2RAB9AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3836934-B1 | PHASE STABLE TOPICAL COMPOSITION COMPRISING ACYCLOVIR AND HYDROCORTISONE | ILKO ILAC SANAYI VE TICARET ANONIM SIRKETI (TR) | 2023-06-21 | — | — | EP | disclosed |