Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.39 |
| ▸ | DTYMK | P23919 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29505992 | 0.80 | MAPK1 (0.60) | MAPK1GPR119AVPR1A | |
| SCHEMBL975814 | 0.80 | MAPK1 (0.60) | MAPK1GPR119AVPR1A | |
| SCHEMBL12473225 | 0.80 | PDE2A (0.52) | MAPK1POLB | |
| SCHEMBL30462275 | 0.78 | POLB (0.47) | MAPK1POLBGPR119GRM5GRM1 | |
| SCHEMBL31000293 | 0.77 | CYP11B2 (0.43) | AVPR1A | |
| SCHEMBL31357123 | 0.76 | MAPK1 (0.53) | MAPK1POLBGPR119AVPR1A | |
| SCHEMBL861264 | 0.76 | POLB (0.45) | MAPK1POLBGPR119GRM5GRM1 | |
| SCHEMBL31170824 | 0.76 | MAPK1 (0.53) | MAPK1POLBGPR119AVPR1A | |
| SCHEMBL1351555 | 0.76 | MAPK1 (0.47) | MAPK1POLBGPR119GRM5GRM1 | |
| SCHEMBL1092663 | 0.75 | POLB (0.44) | POLBGPR119GRM5GRM1DTYMK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478211-B | Novel CGRP receptor antagonist and application thereof | 石家庄迪斯凯威医药科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116478211-A | Novel CGRP receptor antagonist and application thereof | 石家庄迪斯凯威医药科技有限公司 | 2023-07-25 | — | — | CN | disclosed |