Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | DPP4 | P27487 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963616 | 1.00 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1NPSR1HTTDPP4 | |
| SCHEMBL27157357 | 0.84 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1NPSR1HTTDPP4 | |
| SCHEMBL24320108 | 0.84 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1NPSR1HTTDPP4 | |
| SCHEMBL30516932 | 0.84 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1NPSR1HTTDPP4 | |
| SCHEMBL11405894 | 0.82 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1NPSR1HTTL3MBTL1 | |
| SCHEMBL9336356 | 0.79 | NPSR1 (1.00) | SMN1; SMN2ALDH1A1NPSR1L3MBTL1LMNA | |
| SCHEMBL16596932 | 0.79 | HRH3 (0.48) | SMN1; SMN2ALDH1A1NPSR1HTTDPP4 | |
| SCHEMBL1682746 | 0.79 | MAPK1 (0.75) | SMN1; SMN2ALDH1A1NPSR1HTTL3MBTL1 | |
| SCHEMBL30122631 | 0.79 | MAPK1 (0.75) | SMN1; SMN2ALDH1A1NPSR1HTTL3MBTL1 | |
| SCHEMBL540845 | 0.78 | MAPK1 (0.59) | SMN1; SMN2ALDH1A1NPSR1HTTDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143708-A | Polysubstituted benzazepine heteroaryl derivative and application thereof | 四川汇宇制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |