SCHEMBL30454832

SCHEMBL30454832

CSCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C)C(C)C

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ EPHA2 P29317 2/20 0.57
▸ NTSR2 O95665 12/20 0.54
▸ NTSR1 P30989 12/20 0.54
▸ SORT1 Q99523 12/20 0.54
▸ REN P00797 2/20 0.51
▸ SLC6A2 P23975 1/20 0.50
▸ CALCRL Q16602 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30455325 0.89 EPHA2 (0.57) EPHA2
SCHEMBL31257023 0.88 EPHA2 (0.57) EPHA2NTSR2NTSR1SORT1SLC6A2
SCHEMBL13807691 0.87 EPHA2 (0.57) EPHA2NTSR2NTSR1SORT1
SCHEMBL30775524 0.86 F2 (0.56) EPHA2SLC6A2
SCHEMBL31558390 0.86 F2 (0.56) EPHA2SLC6A2
SCHEMBL31307264 0.86 NTSR2 (0.56) EPHA2NTSR2NTSR1SORT1
SCHEMBL30974439 0.86 EPHA2 (0.55) EPHA2NTSR2NTSR1SORT1REN
SCHEMBL9807245 0.85 EPHA2 (0.61) EPHA2NTSR2NTSR1SORT1REN
SCHEMBL10592955 0.85 NTSR2 (0.64) NTSR2NTSR1SORT1
SCHEMBL29786697 0.85 MAPK8 (0.58) EPHA2NTSR2NTSR1SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023122721-A2 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA OREGON STATE UNIVERSITY (US) 2023-06-29 — — WO claimed
US-20240343760-A1 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA OREGON STATE UNIVERSITY (OR) 2024-10-17 — — US disclosed
WO-2023122721-A2 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA OREGON STATE UNIVERSITY (US) 2023-06-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240343760-A1 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA ARGLU1, TPX2, RXFP1 EPHA2 1164/4885NTSR2 124/4885NTSR1 57/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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